Clinical Trials and Research

AAKP's role in Clinical Trials and Market Research

AAKP supports innovation in the kidney space. We are actively involved in market research - to share the patient voice and experience with renal companies and clinical trials  - to create more and better treatment options for kidney patients, so they can achieve their aspirations.

You may have heard the term “clinical trials” but wonder what that means. Is a clinical trial something you can participate in? What do you need to do to get started? We have pulled together some information that you might find helpful as you decide whether you would like to participate in a clinical trial.

View our Clinical Trial Brochure

Learn More About AAKP Awareness Campaigns

Clinical Trials and Market Research Opportunities

Below is a list of the Clinical Trials and Market Research opportunities that AAKP is partnering to raise awareness of.  You can also use the search tool below to be matched to even more opportunities.

Name Description Learn More
HIB-202-101 Lupus Nephritis Study This clinical research study is testing an investigational medication for adults with lupus nephritis. The goal of the study is to see if the study medication can help with symptoms of lupus nephritis and stop the condition from getting worse. Click here to read more about this opportunity.
TwoPlus Study The TwoPlus Clinical Trial is funded by Patient-Centered Outcomes Research Institute (PCORI). The study takes place at ten healthcare systems and more than fifty outpatient dialysis units in the United States. This study takes an unbiased approach to rigorously compare the effectiveness of personalized, incremental hemodialysis and traditional hemodialysis. This study will help patients, care partners, and providers make better decisions about what treatment plan is best for each individual. Studies have found that an incremental treatment plan for hemodialysis (two hemodialysis sessions per week and then three hemodialysis sessions per week) is both safe and effective for patients who have residual kidney function—but not for those who do not have appreciable residual kidney function. Click here to read more about this opportunity.

Watch OnDemand a video about this study.

KYSA-1 The KYSA-1 trial is designed to evaluate if Chimeric Antigen Receptor (CAR) T-cell therapy is safe in people who have active lupus nephritis (LN) and do not get better with standard therapies. CAR T-cell therapy is a type of treatment called immunotherapy. This means it works with your immune system to target B cells in your body. Unhealthy B cells drive inflammation and disease activity in LN. Click here to read more about this opportunity.
SAFE Kidney II The purpose of this study is to evaluate the safety, tolerability, and efficacy of AntiBKV in reducing BK viremia and progression to biopsy-confirmed BKVAN in Kidney Transplant Recipients (KTRs). The study includes two parts. The phase II part will evaluate the safety of AntiBKV in KTRs and establish proof of concept. The phase III part will assess the efficacy of AntiBKV in KTRs. Click here to read more about this opportunity.
SUPERNOVA SUPERNOVA is a pivotal Phase I/III trial for AZD3152, a next-generation long-acting antibody developed to protect vulnerable patients, such as the immunocompromised, from COVID-19. Click here to read more about this opportunity.
KICK Study The KICK Study is a clinical trial testing oral difelikefalin to see if it helps reduce the intensity of itching and the impact that itching has on your quality of life. The oral form of difelikefalin is considered an investigational drug at this time because that form of medication has not been approved by the FDA. An intravenous (IV) form of difelikefalin has been approved by the FDA to treat itching associated with CKD in adults who are undergoing dialysis. The KICK Study will evaluate the medication in its oral (tablet) form to see if it reduces the itching in CKD patients. To be eligible for the study, patients must have advanced CKD (stage 4-5) and experience at least moderate level of itching. Click here to read more about this opportunity.
ConfIdeS Protocol 20-HMedIdeS-17/ ConfIdeS: An open-label, controlled, randomized Phase 3 trial evaluating 12-month kidney function in highly sensitized (cPRA ≥99.9%) kidney transplant patients with positive crossmatch against a deceased donor, comparing desensitization using imlifidase with standard of care. The study is for End-Stage Renal Disease (ESRD) patients that are highly sensitized and are active on the OPTN waiting list for a kidney transplant. Click here to read more about this opportunity.
InnAVasc Arteriovenous Graft Technology If you have kidney failure and are currently undergoing hemodialysis or are expected to require hemodialysis, you may be a candidate for a clinical study evaluating the InnAVasc Arteriovenous Graft – an investigational graft that may make the graft easier to locate under your skin, safer to stick for dialysis, more durable, less likely to bleed after your dialysis session when compared to standard care grafts, and allows for immediate use to reduce catheter time. Click here to read more about this opportunity.
TruGraf Long Term Clinical Outcomes Study The purpose of this study is to evaluate the impact of serial monitoring renal transplant patients with both TruGraf® and TRAC™ on long term outcomes. Click here to read more about this opportunity.




Learn more about kidney disease from fellow patients, healthcare professionals, and the renal community by reading these articles produced for AAKP.
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